Quality of Life
Since the end of the '80s, Annoesjka specialised in Patient Reported Outcomes such as Health Related Quality of Life (HRQoL) and Treatment Satisfaction. Experience is gained in developing and validating new instruments and the selection and use of existing PRO instruments to serve the specified needs.
To realize optimal productlabelling, early strategy development is key in producing valid and marketable phase II and III study results. Anovák-Services can advise in this process and support the optimal labelling of your product. The following publications have resulted from her previous work in this area:

• Health and Quality of Life Outcomes: The Aging Males' Symptoms (AMS) scale. Health and Quality of Life Outcomes, 2003
• Andropause and quality of life. Maturitas, 2002
• User acceptability of the combined contraceptive vaginal ring, NuvaRing. Contraception, 2003
• Development and Validation of an Acceptability and Satisfaction Questionnaire for a Contraceptive Vaginal Ring. PharmacoEconomics, 2004

Real-World Economic Health Outcomes evaluations
By the increased healthcare budget pressure and the introduction of innovative but expensive life-saving therapies, government increasingly adopt a fast process for initial funding, followed by a re-evaluation some years after use of the health care technology. The Netherlands is one of the early adopters of such funding procedure and Annoesjka has played an active role on the industry part in the development of guidance on real-world economic outcomes research. She has also closely monitored international developments at international (policy-makers) meetings and presented at workshops. We are open to discuss with you the requirements for real-life data collection in the Netherlands.